| 產(chǎn)品名稱 | 編號(hào) | 產(chǎn)品說(shuō)明 | 單位 | 單價(jià) | 加入購(gòu)物車 |
| 鏈霉親和素磁珠（300 nm） | 22308-1 | 1 mL, 10 mg/mL, 300 nm | 瓶 | ￥1580.00 | |
| 鏈霉親和素磁珠（300 nm） | 22308-10 | 10 mL, 10 mg/mL, 300 nm | 瓶 | ￥7980.00 | |
| 鏈霉親和素磁珠（300 nm） | 22308-100 | 100 mL, 10 mg/mL, 300 nm | 瓶 | 詢價(jià) |
鏈霉親和素-生物素（SA-Biotin） 系統(tǒng)具有極高的結(jié)合親和力（K =10^-15） ， 在生物領(lǐng)域具有廣泛的應(yīng)用。 BeaverBeads? Streptavidin磁珠表面共價(jià)偶聯(lián)SA蛋白，可高效結(jié)合生物素化抗體、核酸、蛋白等配體分子。本產(chǎn)品采用超順磁性微球，粒徑均一、形貌規(guī)整，有利于方便、快捷地捕獲目標(biāo)分子以及實(shí)現(xiàn)磁性分離。本產(chǎn)品可配套自動(dòng)化設(shè)備進(jìn)行高通量操作。
產(chǎn)品列表
產(chǎn)品信息 | SA磁珠 Cat. #22307 | SA磁珠 Cat. #22305 | SA磁珠 Cat. #22306 | SA磁珠 Cat. #22308 |
游離生物素 （pmol/mg磁珠） | 1100 | 1000 | 800 | / |
生物素化單鏈寡核苷酸(24nt) （pmol/mg磁珠） | 500 | 400 | 400 | 450 |
生物素化IgG （μg/mg磁珠） | 20 | 20 | 15 | 15 |
| 磁珠粒徑 | 1μm | 2μm | 5μm | 300nm |
磁珠濃度 | 10 mg/mL | |||
磁珠表面 | 親水基團(tuán) | |||
保存溶液 | 1×PBS, 含0.1%（w/v）BSA, 0.1%（v/v）proclin-300 | |||
保存條件 | 2~8℃ | |||
保質(zhì)期 | 2年 | |||
產(chǎn)品優(yōu)勢(shì)
? 優(yōu)秀的生物素分子結(jié)合能力
? 良好的穩(wěn)定性
? 快速靈敏的磁響應(yīng)性能
? 可適應(yīng)較為廣泛的實(shí)驗(yàn)條件
圖一、磁珠經(jīng)不同溶液處理后結(jié)合生物素化分子的活性
圖2、磁珠經(jīng)熱處理后結(jié)合生物素化分子的活性
產(chǎn)品應(yīng)用實(shí)例
1、檢測(cè)Biotin標(biāo)記的兔IgG
 | BeaverBeads? Mag SA磁珠可檢測(cè)濃度低至6.25ng/mL的Biotin-IgG。 |
2、檢測(cè)Biotin標(biāo)記DNA探針
| BeaverBeads? Mag SA磁珠可檢測(cè)濃度低至6.25fmol/mL的Biotin-DNA 探針，且具有較低的本底吸附。 |
文獻(xiàn)參考：doi:10.1038/ni.3229
引用文獻(xiàn)：
1. Immunity of turbot Induced by inactivated vaccine of from the perspective of DNA methylation. Frontiers in immunology, 2023.
2. Populus euphratica GLABRA3 Binds PLDδ Promoters to Enhance Salt Tolerance. International journal of molecular sciences, 2023.
3. Selection and electrochemical-sensor application of an DNA-aptamer for methyl parathion detection. Analytica chimica acta, 2023.
4. Efector protein Hcp2a of avian pathogenic Escherichia coli interacts with the endoplasmatic reticulum associated RPL23 protein of chicken DF-1 fbroblasts. 2023.
5. Immunity of turbot Induced by inactivated vaccine of Aeromonas salmonicida from the perspective of DNA methylation. Frontiers in Immunology, 2023.
6. An integrated magneto-fluorescent nanosensor for rapid and sensitive detection of tumor-derived exosomes. Sensors and Actuators B: Chemical, 2023.
7. A convenient fluorescent/electrochemical dual-mode biosensor for accurate detection of Pb2+ based on DNAzyme cycle. Bioelectrochemistry, 2023.
8. An Ultrasensitive Colorimetric Foodborne Pathogenic Detection Method Using a CRISPR/Cas12a Mediated Strand Displacement/Hybridization Chain Reaction. Journal of agricultural and food chemistry, 2023.
9. Dual recognition strategy for the rapid and precise detection of Bacillus cereus using post-modified nano-MOF and aptamer. Sensors and Actuators B: Chemical, 2023.
10. Jasmonate activates a CsMPK6-CsMYC2 module that regulates the expression of β-citraurin biosynthetic genes and fruit coloration in orange (Citrus sinensis). The Plant cell, 2023.
11. Nanozyme-catalysed CRISPR-Cas12a system for the preamplification-free colorimetric detection of lead ion. Analytica Chimica Acta, 2023.
12. A fully human connective tissue growth factor blocking monoclonal antibody ameliorates experimental rheumatoid arthritis through inhibiting angiogenesis. BMC biotechnology, 2023.
13. SERS-based immunomagnetic bead for rapid detection ofH5N1 influenza virus. Influenza and other respiratory viruses, 2023.
14. The role of post-transcriptional modification on a new tRNAIle(GAU) identified from Ganoderma lucidum in its fragments’ cytotoxicity on cancer cells. International Journal of Biological Macromolecules, 2023.
15. Dhx33 promotes B-cell growth and proliferation by controlling activation-induced rRNA upregulation. Cellular & molecular immunology, 2023.
16. Rapid detection of Pseudomonas aeruginosa based on lab-on-a-chip. Anal Chim Acta 2022 Jan 02;1189.
17. A tRNA-derived fragment from Chinese yew suppresses ovarian cancer growth via targeting. Mol Ther Nucleic Acids 2022 Mar 08;27.
18. An Ultrasensitive Strand Displacement Signal Amplification-Assisted Synchronous Fluorescence Assay for Surface Proteins of Small Extracellular Vesicle Analysis and Cancer Identification. Anal Chem 2022 01 18;94(2). DOI: 10.1021/acs.analchem.1c04122.
19. Antitumor Activities of tRNA-Derived Fragments and tRNA Halves from Non-pathogenic Escherichia coli Strains on Colorectal Cancer and Their Structure-Activity Relationship. mSystems 2022 Apr 26;7(2).
20. Colorimetric liquid crystal-based assay for the ultrasensitive detection of AFB1 assisted with rolling circle amplification. Analytica Chimica ActaVolume 1220, 2022.
21. Costunolide alleviates atherosclerosis in high-fat diet-fed ApoE?/? mice through covalently binding to IKKβ and inhibiting NF-κB-mediated inflammation. Acta Pharmacol Sin 2022 Jun 16.
22. Enzyme-Free Colorimetric Method for Fast Detection of Pik3ca Gene Mutation by Praseodymia Nanorods. 2022.
23. Gasdermin D mediates doxorubicin-induced cardiomyocyte pyroptosis and cardiotoxicity via directly binding to doxorubicin and changes in mitochondrial damage. Transl Res 2022 May 08.
24. Insight into mechanisms of pig lncRNA FUT3-AS1 regulating E. coli F18-bacterial diarrhea. PLoS Pathog 2022 06;18(6).
25. Noninvasive Prognosis of Postmyocardial Infarction Using Urinary miRNA Ultratrace Detection Based on Single-Target DNA-Functionalized AuNPs. ACS Appl Mater Interfaces 2022 Jan 26;14(3). DOI: 10.1021/acsami.1c17883.
26. On-chip classification of micro-particles using laser light scattering and machine learning. Chinese Chemical Letters. 2022,33(04).
27. Rapid detection of Pseudomonas aeruginosa based on lab-on-a-chip platform using immunomagnetic separation, light scattering, and machine learning. Analytica Chimica Acta, Volume 1189, 2 January 2022, 339223. DOI: 10.1016/j.aca.2021.339223.
28. Structure-switching aptamer triggering signal amplification strategy for tobramycin detection based on hybridization chain reaction and fluorescence synergism. Talanta 2022 Jun 01;243.
29. The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4 T cells by preventing ferroptosis. Nat Immunol 2022 02;23(2).
30. Themis is indispensable for IL-2 and IL-15 signaling in T cells. Sci Signal 2022 02 15;15(721). DOI: 10.1126/scisignal.abi9983.
31. Rapid Naked-Eye Tracking of On-Cell Phenotype Based on Dual-Aptamer-Weaved Cascade Assembly of Nanostructures. Analytical chemistry, 2021, 93(32): 11159-11166. DOI: 10.1021/acs.analchem.1c01668.
32. Stick, stretch, and scan imaging method for DNA and filaments. RSC Advances, 2021, 11(57): 36060-36065. DOI: 10.1039/D1RA07067C (Paper) RSC Adv., 2021, 11, 36060-36065.
33. Aptamer-Based Dual-Functional Probe for Rapid and Specific Counting and Imaging of MCF?7 Cells；Anal. Chem. 2018, 90, 2355?2361.
34. The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells；Immunity 47, 538–551，DOI：10.1016/j.immuni.2017.08.011.
35. Fatty Acid Elongase‐7 Is Regulated Via SP1 and Is Involved in Lipid Accumulation in Bovine Mammary Epithelial Cells；Journal of Cellular Physiology，DOI 10.1002/jcp.26255.
36. The transcription factor TCF-1 initiates the differentiation of TFH cells during acute viral infection；NATURE IMMUNOLOGY 卷: 16 期: 9 頁(yè): 991-999 出版年: SEP 2015.
